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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLTCL1 All Species: 50.91
Human Site: Y504 Identified Species: 93.33
UniProt: P53675 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53675 NP_009029.3 1640 187030 Y504 Q F Q K I V L Y A K K V G Y T
Chimpanzee Pan troglodytes XP_001154119 1640 186911 Y504 Q F Q K I V L Y A K K V G Y T
Rhesus Macaque Macaca mulatta XP_001108544 1639 187872 Y504 Q V Q K I V L Y A K K V G Y T
Dog Lupus familis XP_534763 1673 189990 Y504 Q F Q K I V L Y A K K V G Y V
Cat Felis silvestris
Mouse Mus musculus Q68FD5 1675 191538 Y504 Q V Q K I V L Y A K K V G Y T
Rat Rattus norvegicus P11442 1675 191580 Y504 Q V Q K I V L Y A K K V G Y T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509659 1675 191558 Y504 Q V Q K I V L Y A K K V G Y T
Chicken Gallus gallus XP_415060 1672 190998 Y504 Q F Q K I V L Y A K K V G Y T
Frog Xenopus laevis NP_001085860 1675 191412 Y504 Q V Q K I V L Y A K K V G Y T
Zebra Danio Brachydanio rerio XP_699126 1677 191618 Y504 Q F Q K I V L Y A K K V G Y T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29742 1678 191159 Y505 Q F Q K I V L Y A K K V N Y T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34574 1681 191524 Y502 Q F D K I V M Y A K R V G F Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22137 1653 187216 Y508 Q F E K I I P Y C Q K V G Y Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 84.6 90.6 N.A. 83 82.9 N.A. 82.9 88.1 82.5 83.3 N.A. 75.3 N.A. 67.8 N.A.
Protein Similarity: 100 99.6 93.2 94.8 N.A. 91.5 91.4 N.A. 91.3 93.9 91.2 91.1 N.A. 87 N.A. 82.1 N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. 93.3 100 93.3 100 N.A. 93.3 N.A. 66.6 N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. 93.3 100 93.3 100 N.A. 93.3 N.A. 86.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 48.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 69.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 60 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 93 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 62 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 93 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 100 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 100 0 0 0 0 0 93 93 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 85 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % P
% Gln: 100 0 85 0 0 0 0 0 0 8 0 0 0 0 16 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 77 % T
% Val: 0 39 0 0 0 93 0 0 0 0 0 100 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 100 0 0 0 0 0 93 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _